dcraig01

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dcraig01
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  • Hello, Regarding the last paragraph of the post: "At the Broad Institute, we typically make a standard PON for a given version of the pipeline (corresponding to the combination of all protocols used in production to generate the sequence data,…
  • Hi bhanu, I'm wondering if there's either (a) a way to rename the header so that it matches my input (I don't know what the name in the BAM header is, or (b) have MuTect ignore the differing headers (by deleting them). Thanks
  • Hi @shlee Thanks for directing me to these; they're very helpful! Does this mean that a new panel of normals must be sequenced simultaneously for each experiment (specific to the sample type), or is there a file that contains the frequencies for a…
  • Hi Geraldine, I would like to compare the variant frequency at each nucleotide site for a given exon without using a matched normal sample. The idea being that any variant frequency that is significantly different from the background sequencing err…