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How to split positive site to TPs (true positive) and FPs (false positive)?

haopenghaopeng ChineseMember
Dear GATK team,
I wondered how do you divide sites into TPs and FPs. Why there were FPs sites in the tranches plots if the sites were scored by Gaussian model? Was there another step to divide positive sites into true and false except the scoring VQSLOD step? If there was, and how?
I found that there might be a useful answer in forum as what I showed in attachment. But the link had failed.

Best Answer


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