Test-drive the GATK tools and Best Practices pipelines on Terra

Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.

UV mutagenesis hotspots

How can I use GATK to identify mutation hotspots on a genome? What tools do I use? I have an organism that I UV mutagenized and resequenced and now I want to identify regions on the genome that were more prone to mutation.



  • Geraldine_VdAuweraGeraldine_VdAuwera Cambridge, MAMember, Administrator, Broadie admin

    GATK can only give you the mutations themselves. To do an analysis on mutation hotspots you will need to use some other software, I recommend looking in the literature to see what people use for this. Good luck!

Sign In or Register to comment.