Heads up:
We’re moving the GATK website, docs and forum to a new platform. Read the full story and breakdown of key changes on this blog.
We’re moving the GATK website, docs and forum to a new platform. Read the full story and breakdown of key changes on this blog.
Notice:
If you happen to see a question you know the answer to, please do chime in and help your fellow community members. We encourage our fourm members to be more involved, jump in and help out your fellow researchers with their questions. GATK forum is a community forum and helping each other with using GATK tools and research is the cornerstone of our success as a genomics research community.We appreciate your help!
If you happen to see a question you know the answer to, please do chime in and help your fellow community members. We encourage our fourm members to be more involved, jump in and help out your fellow researchers with their questions. GATK forum is a community forum and helping each other with using GATK tools and research is the cornerstone of our success as a genomics research community.We appreciate your help!
Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
HaplotypeCaller error: A fatal error has been detected by the Java Runtime Environment

Hi,
When I am using HaplotypeCaller on a recently updated system, I always got an error message like this:
#
A fatal error has been detected by the Java Runtime Environment:
#
SIGSEGV (0xb) at pc=0x00007ff0d6126ce9, pid=30388, tid=0x00007ff10e748700
#
JRE version: Java(TM) SE Runtime Environment (8.0_131-b11) (build 1.8.0_131-b11)
Java VM: Java HotSpot(TM) 64-Bit Server VM (25.131-b11 mixed mode linux-amd64 compressed oops)
Problematic frame:
C [libVectorLoglessPairHMM442890693276836996.so+0x1bce9] LoadTimeInitializer::LoadTimeInitializer()+0x1669
Does anybody know what is the cause of the problem? Are there any fix to it?
Thanks,
Answers
Hi @ktrp90,
short question do you run the HaplotypeCaller with the -nct Flag (multi-threaded mode)? Set nct to 1 and try again. It is a known problem that the HTC sometimes crash in multi-threaded mode. Maybe they will fix it in GATK4.
Greetings EADG
@ktrp90
Hi,
This thread has some tips.
-Sheila