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Which tool to detect variants in tumor cell line samples without matched normal?

Gio83Gio83 ItalyMember

I am analyzing Exome data from cancer cell lines, without normal sample. Can I use Mutect? If yes which parameters should I set?
Otherwise can I use GATK?
I now that maybe there are a lot of thread about this discussion but I am not able to find a final decision.

Best Answer


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