We've moved!
This site is now read-only. You can find our new documentation site and support forum for posting questions here.
Be sure to read our welcome blog!

VQSR - overlapping training sets

Hi,

when I have multiple training sets for VQSR,
what happens with overlapping variants between these two sets?
Especially when the two sets have different priors attached.

Example from Best Practices:
I have HapMap with prior Q15 and
1000G with prior Q10.
How will a variant influence the model when being in both sets?
I would expect that only the highest prior will be used.

Thanks,
Alexander

Best Answer

Answers

Sign In or Register to comment.