Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
GATK v3.0 not forwarding GVCF genotype annotations?
First of all, I'm very excited about v3.x GATK, you guys and gals on the GATK Team are doing awesome work!
I have a question: How do I get CombineGVCFs to forward the sample-level annotations calculated by HC with the --emitRefConfidence GVCF option enabled? I tried passing the same annotation flags to CombineGVCFs that I passed to HC, but none of the annotations beyond the standard set were incorporated. Annotations such as StrandBiasBySample require access to the underlying reads and forwarding these annotations to the CombineGVCFs output would be less prohibitive than running VariantAnnotator on my 20 WGS datasets...