Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
memory used by DepthOfCoverage
I tried to use DepthOfCoverage to figure out the coverage of 50 whole exome sequencing data. It works fine for single sample, however, the program always complained about memory issue, even I provide 100 GB as "-Xmx100g". Any suggestions for the problem? There is a option "--read_buffer_size", which seems to be helpful, how should set the value ?