If you happen to see a question you know the answer to, please do chime in and help your fellow community members. We appreciate your help!
Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
the dbsnp input in MuTect
In MuTect2, the dbsnp is not a must input. If I do not provide dbsnp file when running MuTect2 on exome data, will MuTect2 treat all the sites as non-dbsnp sites, and use threshold of 2.2 in variant classification? If this is the case, how does it affect the sensitivity? Thanks for help.