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the dbsnp input in MuTect
In MuTect2, the dbsnp is not a must input. If I do not provide dbsnp file when running MuTect2 on exome data, will MuTect2 treat all the sites as non-dbsnp sites, and use threshold of 2.2 in variant classification? If this is the case, how does it affect the sensitivity? Thanks for help.