If you happen to see a question you know the answer to, please do chime in and help your fellow community members. We encourage our fourm members to be more involved, jump in and help out your fellow researchers with their questions. GATK forum is a community forum and helping each other with using GATK tools and research is the cornerstone of our success as a genomics research community.We appreciate your help!

Test-drive the GATK tools and Best Practices pipelines on Terra

Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.

panel of normals tissue origin

2nelly2nelly SwitzerlandMember

Hi all,

I am thinking to build a panel of normal samples using MuTect2 in order to use it for somatic variant calling in mouse tumors. So, my question is: can this panel be a fusion of samples coming from different types of tissue or should come from the same type? Suppose doesn't matter.

Thank you in advance!

Issue · Github
by Sheila

Issue Number
Last Updated
Closed By

Best Answer


  • 2nelly2nelly SwitzerlandMember

    I was thinking to use it in order to exclude rare germline variants.
    Of course all my candidate samples for PON are coming from healthy mice.

    So, thanks for your reply Geraldine
    Keep up the good work!

Sign In or Register to comment.