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Should I combine GVCFs
For previous versions of the GATK, I ran across a forum post recommending that when genotyping large numbers of GVCFs (over 2 or 300) I should first combine them with the CombineGVCFs call. Otherwise, I could see a huge slowdown in joint genotyping.
For version 3.4 is this still the recommended practice, or has this issue been addressed?