Realignment intervals distribution
I was just wondering what you guys thought of my realignment intervals length distribution.
This is 30Mb from a single diploid sample without prior indel position information. Approximately 60,000 events , i.e. one every fifty bases seems like a lot.
How indicative of true indels is the data from TargetCreator and IndelRealigner? Guess I'll have to check with the ug-vcf calls...
Across the genome, distribution of 'all' events is uniform.
Does multi-sample realignment improve the accuracy or efficiency of the realignment process ?