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Simple way to check ID of samples, like a sequence identifier?


I am wondering if there is a simple way to positively check that our sequencing samples did not somehow get 'mixed up.'

To clarify, suppose we sequence a batch of several samples and two of them are accidentally switched, or the adapters are switched.

Once we receive sequencing data, I don't believe there is any way to positively confirm that a set of reads actually belongs to a specific DNA sample other than to make sure that nothing is mixed up during the preparation process.

Is there a simple way to 'double check' to achieve this, like a quick genotype test on the DNA sample that can be confirmed in the sequence data, some kind of sequence identifier? Hopefully this concern has come up before and there is a reasonable way to address it.

Thank you

Best Answer


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