What should I do if I don't have cosmic.vcf and dbsnp.vcf when using muTect?
Hi @kcibul ,
I have some quires about muTect when using it.
For mammals such as human, there are dbSNP and COSMIC SNP database. But in plant, there aren't such database, at least no COSMIC database. I know there is no "tumor" in plant. But my data is similar to data from tumor.
So what I want to know are: 1) What are dbSNP and COSMIC SNPs used for in muTect? 2) Can I still use muTect under the situation I mentioned?