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I only have NGS data from 20 person, the data set is too small to do variant recalibration. Therefore,I want to merge the whole exome data from 1000 Genome.
**But my NGS data had been use " -L argument " to choose the intervals of 100 gene,so should whole exome data from 1000 Genome also have to use " -L argument " to choose 100 gene before I merge the data with NGS data from 20 person? **
Thanks for help