This site is now read-only. You can find our new documentation site and support forum for posting questions here.
Be sure to read our welcome blog!
Use of Population frequencies in Contamination Estimation?
I am trying to understand the statistics and methodology behind ContEST.
However, I am not able to understand why Population Frequency is required in the first place. What is the role of HapMap_19_pop_freq.vcf file's role in contamination estimation?
Looking forward to a reply.