Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
Does the GATK read the reference from the disk frequently?
Uh..Does the GATK read the reference such as hg19 from the disk each time it runs some tools?
As the GATK will run many tools such as RealignerTargetCreator, IndelRealigner, BaseRecalibrator in a variant detection pipeline, if it read hg19 from the disk every time, it will be time-consuming...