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Maximum size for HaplotypeCaller

eflynn90eflynn90 Washington DCMember

I'm running HaplotypeCaller, and I was wondering what a recommended cohort size was. Would 30 to 40 families (100 to 150 individuals) be too large? Is there a maximum recommended size for number of independent alleles/number of individuals? How does the run time scale with additional individuals?

Thanks,
Elise

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