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DP different in IGV and GVCF file

Hello everyone,

I have aligned my exome sample using Dragen Germline Application on Basespace which resulted in corresponding GVCF and .bam files. I was interested in a particular variant on chr11, when I see this variant in the GVCF file I see that DP is 89 where as when I load the .bam file in IGV I see only 68 reads. I have also tried removing the filters (duplicate and vendor failed) in IGV and I am still getting depth as 72. Can you please explain me as to why these are getting filtered.


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