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Using Mutect2 on FFPE samples to call germline variants
I've followed the topics on Mutect2 and its way to perform reduction of FFPE artifacts from tumor tissue.
However my task is a little different: I would like to use Mutect2 and its way to remove FFPE artifacts in "normal" tissue, to assess germline variants. It is possible to clean from artifact using Mutect2 and subsequently filter out the possible germline variants? And how can I do it?
Thanks for all the help