Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
[GATK 188.8.131.52] how OPTIMAL_F_SCORE is calculated in FilterMutectCalls
I am using GATK184.108.40.206 FilterMutectCalls after applying Mutect2 with default option. I found --threshold-strategy OPTIMAL_F_SCORE is the actual filtering threshold to judge PASS or other. How is the score being calculated in the tool? Considering multiple values like nlod, tlod etc?