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Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
Potential for merging GenomeDBs or adding to an existing database
I have adopted using GenomicsDBImport for my workflows involving ~2500 samples to begin. This data structure works well and I am very happy it was implemented. However my data is such that I will be adding more samples every 2-3 months or so for the foreseeable future. It becomes very cumbersome and space-prohibitive to manage both gVCFs and a GenomeDB, as well immensely time consuming to include all samples again and again to maintain this. Is there a way now, or a plan to add new samples to existing data, or merge GenomeDBs? I anticipate this will become a common need.