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Is DP the right criteria to be used in whole exome sequencing.

I have whole exome sequencing data from multiple mice. I have performed GATK4.1 pipeline and for recal i have used dbSNP142 and also snpeff. Can I consider DP=100 as the minimum value to filter the resultant SNPs found. When I keep the coverage minimum to DP= 50, i end up with more SNPs. But I end up having less SNPs when i go higher in DP value.

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