Test-drive the GATK tools and Best Practices pipelines on Terra


Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.

Mutect1 multi-allelic cases

ersenkavakersenkavak TurkeyMember
edited March 4 in MuTect v1

Hello,
We have worked hard to figure this out.
By default, or by using any parameters, Mutect1 does not catch multi-allelic cases at a single position. It seems to pick one of the alternate alleles at every position (randomly?). As in mutect2, one expects ploidy like parameter. We need to detect every alternate allele at that position, as somatic analysis requires this.

Do you have an idea? How should one use Mutect1 for detecting multiallelic cases?

Thanks

Post edited by ersenkavak on
Tagged:
Sign In or Register to comment.