A strange INDEL with AD and DP are zeros

btrspg

Hi there,

Here is the mutation.

4   5858712 .   G   GTTATCACCACTATCATTATCACCCCACCACCATCATCACCATCACCACCACCACCATCATCATTACTAACATTATCACCACCACCACCATCACCACCATCATCACCACCGCCACCATCCACTATCATCACCACCATCCACTA,GTTATCACCACTATCATTATCACCCCACCACCATCATCACCATCACCACCACCACCATCATCATTACTAACATTATCACCACCACCACCATCACCACCATCATCACCACCGCCACCATCCACTATCATCACCACCATCCACTATCATCACCACCATCCACTA  1155.73 .   AC=1,1;AF=0.500,0.500;AN=2;DP=15;ExcessHet=3.0103;FS=0.000;MLEAC=1,1;MLEAF=0.500,0.500;MQ=60.00;SOR=0.693   GT:AD:DP:GQ:PL  1/2:0,0,0:0:99:1193,321,251,263,0,191

Why it call out the mutation but the AD and DP in FORMAT are both zeros. Is this mutation can be trusted or not?

bshifaw

Hi @btrspg ,

This discussion should help clear things up : Allele Depth (AD) is lower than expected
Let us know if you have any more questions.

bshifaw

Hi @btrspg ,

This discussion should help clear things up : Allele Depth (AD) is lower than expected
Let us know if you have any more questions.

btrspg

Thanks, it real helps me.