Test-drive the GATK tools and Best Practices pipelines on Terra
Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
about the info from read group
Hi, I have two bam files from one case and one control. They were both mapped with bwa. In their bam files, their readgroup tags are with different sample ID (SM), but with the same library ID (LB).
I then fed the two bam files into GATK together for realignment, and the output is a merged bam for the two samples. I am just a bit unsure, if the two samples with the same LB id will affect the downstream variant calls? can the caller can distinguish them by their different sample IDs?
Thank you very much for your kind guidance!