Test-drive the GATK tools and Best Practices pipelines on Terra
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Set up pipeline for WES and WGS
working with WES and WGS data (GATK 220.127.116.11) I would like to know the set up differents between their pipelines for germline and somatic variant discovery.
I saw that I have to use two different interval lists (-L, BQSR & HC), as also in the VQSR step I have to exclude the -an DP option in the WES pipeline .
Moreover, in the site it is reported that there is a WES pipeline with hg19 and a WGS pipeline with hg38, in which the last one is in the Best Practices pages.
Could you provide me any link about the WES set up.