If you happen to see a question you know the answer to, please do chime in and help your fellow community members. We encourage our fourm members to be more involved, jump in and help out your fellow researchers with their questions. GATK forum is a community forum and helping each other with using GATK tools and research is the cornerstone of our success as a genomics research community.We appreciate your help!

Test-drive the GATK tools and Best Practices pipelines on Terra

Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.

Does Base quality recalibration step is needed to process the bam file?

I'm using GATK 4.0 base quality re-calibration really important to process a bam file?
Can i know what are new features are introduced in GATK 4.0 when compare to older versions ?
If I'm using GATK 4.0 whether it does automatically base-calibration step if i supplied a bam file ?


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