how to extract unique variants from GVCF?

HESmithHESmith National Institutes of HealthMember

I have a GVCF (generated using HaplotypeCaller -ERC GVCF) of 36 samples and would like to determine the (potentially de novo) variants that are unique to each sample. Short of creating 36 N-1 GVCFs for discordance testing, or individual sample VCFs for subtraction, is there a straightforward method to obtain the desired information?


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