This site is now read-only. You can find our new documentation site and support forum for posting questions here.
Be sure to read our welcome blog!
how to extract unique variants from GVCF?
I have a GVCF (generated using HaplotypeCaller -ERC GVCF) of 36 samples and would like to determine the (potentially de novo) variants that are unique to each sample. Short of creating 36 N-1 GVCFs for discordance testing, or individual sample VCFs for subtraction, is there a straightforward method to obtain the desired information?