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Funcotator error

zwzhangzwzhang Member, Broadie
edited June 2018 in Ask the GATK team

Hi, GATK team

I ran into a problem recently coming from Funcotator. I initially run Mutect2 coupled with Funcotator on FireCloud, GATK version, but it throw out some error. And I also tried run Funcotator locally and it produces the almost identical error, see below

[June 6, 2018 1:47:32 PM EDT] org.broadinstitute.hellbender.tools.funcotator.Funcotator done. Elapsed time: 12.63 minutes.
java.lang.StringIndexOutOfBoundsException: String index out of range: -61
    at java.lang.String.substring(String.java:1967)
    at org.broadinstitute.hellbender.tools.funcotator.dataSources.gencode.GencodeFuncotationFactory.createUtrFuncotation(GencodeFuncotationFactory.java:1088)
    at org.broadinstitute.hellbender.tools.funcotator.dataSources.gencode.GencodeFuncotationFactory.createGencodeFuncotationOnTranscript(GencodeFuncotationFactory.java:601)
    at org.broadinstitute.hellbender.tools.funcotator.dataSources.gencode.GencodeFuncotationFactory.createFuncotationsHelper(GencodeFuncotationFactory.java:529)
    at org.broadinstitute.hellbender.tools.funcotator.dataSources.gencode.GencodeFuncotationFactory.createFuncotationsOnVariant(GencodeFuncotationFactory.java:276

I know Funcotator is still in beta version, but want to ask you help me debug this problem and I am also wondering is there any more stable Funcotator.



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