How to perform AddorReplaceReadGroups
I have inherited whole exome sequencing data for paired normal and tumor samples with the aim of identifying somatic variants. I have already performed the alignment to hg38, converted sam files to bam files and now would like to AddorReplaceReadGroups. I do not have the information on how many libraries were prepared. Samples were multiplexed i.e. groups of 3 - 10 samples were run per lane of the flow cell. Would it be appropriate to assume that one library was prepared per sample?