Heads up:
We’re moving the GATK website, docs and forum to a new platform. Read the full story and breakdown of key changes on this blog.
If you happen to see a question you know the answer to, please do chime in and help your fellow community members. We encourage our fourm members to be more involved, jump in and help out your fellow researchers with their questions. GATK forum is a community forum and helping each other with using GATK tools and research is the cornerstone of our success as a genomics research community.We appreciate your help!

Test-drive the GATK tools and Best Practices pipelines on Terra

Check out this blog post to learn how you can get started with GATK and try out the pipelines in preconfigured workspaces (with a user-friendly interface!) without having to install anything.
We will be out of the office for a Broad Institute event from Dec 10th to Dec 11th 2019. We will be back to monitor the GATK forum on Dec 12th 2019. In the meantime we encourage you to help out other community members with their queries.
Thank you for your patience!

MNP calling problem in GATK4 Mutect2 beta

I tried to use GATK4 Mutect2 to call somatic mutations and found some weird MNP results:
chr2 157214886 GT TT
chr4 130772884 CGTGT TGTGT
chr4 145617203 TAAA AAAA
chr5 7857891 CAA AAA
chr5 30904821 AT TT

It sounds these variants should be simple SNPs however called as MNP here. Is it a bug in variant calling of Mutect2? Does GATK4 Mutect2 support MNP calling now?


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