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MuTect2 beta --germline_resource file

Hi,
I'm new in using MuTect2 :p
I'm a bit confused that the gnomAD file provided on gnomad.broadinstitute.org/downloads is about three times larger than the gnomAD file provided on ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/beta/Mutect2/af-only-gnomad.raw.sites.b37.vcf.gz ?
is there any difference between these two files ? could the difference affect the output of MuTect2??

Thx in advance :)

Answers

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