Calling copy number from WGS data using PON from different platform
Hi, I'm trying to call somatic copy number form WGS data using the workflow laid out in cnv_somatic_copy_ratio_bam_workflow.wdl
However, I do not have a panel of normals for the sample. The data was sequenced using HiSeq 4000 with 100bp reads. Would it be reasonable to construct a panel of normals from publicly available data (1000 genomes project) that was sequenced using HiSeq 2000 and has 90bp reads?