Running ASE Read counter on WXS

skhalid7skhalid7 GatechMember

Hi
I wanted to ask if I can use ASE read counter on WXS data, instead of RNA seq. Would it give me the number of times a particular SNP has been observed on the DNA level? And is it correct to interpret the results that way?

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  • Geraldine_VdAuweraGeraldine_VdAuwera Cambridge, MAMember, Administrator, Broadie admin

    Are you looking for allelic depth observed in sequencing?

  • skhalid7skhalid7 GatechMember
    edited August 2017

    No I'm hoping to use it as a proxy for copy number alterations per allele (does allele A seem to have more copies than Allele B ), need it for a quick analysis.

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