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how to set the value "--contamination_fraction_to_filter" of Mutect2 ?

HI,
what's the meanning of the Mutect option "--contamination_fraction_to_filter " ?
how to set that value ?
it's value of ContEst result ? I know ContEst is used to evaluate the cross-individual contamination ,and the result is bigger than 5% threhold,showing there is a servious contamination .

Answers

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