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  • dgewing
    Thank you for your response!

    I am sorry for not creating a more concise and complete question; I hope you will give me a 2nd chance.

    I understand that the AD provides the "unfiltered" allele depth, i.e. the number of reads that support each of the reported alleles and that the GT field provides the genotype of the sample and that "0" is the REF allele and "1" represents the first ALT allele. (1/1 is a homozygous alternate sample--0/0 is a homozygous reference sample)

    My question was seeking understanding of the combination of the two pieces of "coupled" data: GT and AD

    If the sample is homozygous alternate (1/1) and the AD is 14,4;how do I interpret those 2 pieces of data when they are for the same "position" (on the same line or on the same record or for the same position)??

    Again I apologize for not making my question clear, and hope you have a happy Thanksgiving or a happy 28th of November if you are not in the US.


    dg
    November 2019
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