Hello @Olu -
If you go to our Featured Workspaces tab and click on the workspace that you wish to run on your samples, you will see within the Dashboard tab some cost analysis information that we collected based on the example samples we tested. From this information (size of files etc) you should be able to extrapolate to your samples and come up with a general idea of how much it might cost.
@Olu You can follow this tutorial to convert your fastq files to uBAM in the event that the analyses that you want to perform on FireCloud require a uBAM input.
Yes, you should be able to convert your fastq files to the uBAMs by following the tutorial.
For costs, you will have to also factor in the size of your sample. In the example we provided, we noted the size of the NA12878 sample and the costs associated with each Tool based on the size. If your file is also of similar size, you can expect that this estimate still stands. Please keep in mind that these numbers are estimates since there are variables we cannot account for such as your storage costs after analysis etc.