bertrand

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bertrand
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Location
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Bertrand Haas

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  • Hi Richard, 4.a) The jitter to MQ is new but jitter to SOR, InbreedingCoeff, FS, and HaplotypeScore have been set in previous release and remain at the same value (0.01 * Normal(0,1)). This alleviates some of the problem having a lot of variants w…
  • Hi Richard, 1) No, the new jitter feature happens anyway even if MQ is not logit transformed. This is to avoid having a huge pile-up of capped MQ's (transformed or not). Such a pile-up on a single value has ill-effects on VQSR's underlying algorit…