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GATK VariantAnnotator error

GenomeHackerGenomeHacker BostonMember Posts: 5

I am getting a strange error when running the VariantAnnonator - does anyone know what this is about?

I am running it as
java -jar GenomeAnalysisTK.jar -T VariantAnnotator -R ucsc.hg19.fasta --variant result.vcf -comp:COSMIC CosmicMutants.vcf -resource CosmicMutants.vcf -E resource.ID -alwaysAppendDbsnpId -o annotated.vcf

and the error is

WARN 17:22:19,963 AbstractVCFCodec - Allele detected with length 1133370 exceeding max size 1048576 at approximately line 78827, likely resulting in degraded VCF processing performance
WARN 17:22:20,037 AbstractVCFCodec - Allele detected with length 1133370 exceeding max size 1048576 at approximately line 78828, likely resulting in degraded VCF processing performance
WARN 17:22:20,111 AbstractVCFCodec - Allele detected with length 1133370 exceeding max size 1048576 at approximately line 78827, likely resulting in degraded VCF processing performance
....

My vcf file is not that long...but I have looked in CosmicMutants.vcf, and it seems normal to me.

Answers

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