The current GATK version is 3.6-0
Examples: Monday, today, last week, Mar 26, 3/26/04

Howdy, Stranger!

It looks like you're new here. If you want to get involved, click one of these buttons!

Powered by Vanilla. Made with Bootstrap.
Register now for the upcoming GATK Best Practices workshop, Nov 7-8 at the Broad in Cambridge, MA. Open to all comers! More info and signup at

Depth in multisample calling

meharmehar Posts: 95Member


I have used GATK for multi sample SNP calling, the total depth DP at the variant site does not seem to be the same when the individual depths are summed up for few of the variants. For example, for the below shown variant site, DP=24 in the INFO column and from the FORMAT column depth= 3+3+8+2=16.
chr1 3015369 . C A 39.22
AC=4;AF=1.00;AN=4;DP=24;Dels=0.00;FS=0.000;HaplotypeScore=0.0000;MLEAC=4;MLEAF=1.00;MQ=6.96;MQ0=21;QD=2.45;SB=-2.321e+01 GT:AD:DP:GQ:PL ./. 1/1:3,3:6:6:48,6,0 1/1:8,2:10:3:25,3,0

Could someone give an explanation for differences in depths?


Best Answer


Sign In or Register to comment.