Service note: Geraldine will be on vacation March 7-16. During this time, the team may not be able to answer your questions and comments in the forum. Regular service will resume March 17. Apologies for any inconvenience!
Adjusting priors for heterozygosity for pooled samples in UnifiedGenotyper
Hi to all,
I am calling variants in a pooled sample of 3 human samples, using UnifiedGenotyper and a ploidy of 6 and I was wondering if it is necessary to adjust the heterozygosity rate (--heterozygosity) to be 0.003 instead of the default of 0.001, or if the model used in the pooled sample calling already takes this into account.Thanks a lot,
0 · ·