Bug Bulletin: The GenomeLocPArser error in SplitNCigarReads has been fixed; if you encounter it, use the latest nightly build.

Combining PhaseByTransmission and ReadBackedPhasing

BerntPoppBerntPopp Posts: 47Member

Hello GATK Team,

there are currently two walkers for phasing in the GATK PhaseByTransmission and ReadBackedPhasing. Because of their different information source (PhaseByTransmission has the called VCF file, ReadBackedPhasing the BAM files) these can produce different or complementary genotypes. There used to be a walker for this job "MergeAndMatchHaplotypes" but it seems to be discontinued.

What is the current recommendation for Trios? Only use PhaseByTransmission?

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