Service note: Geraldine is on vacation this week; other members of GSA will be responding to questions, but they have a lot of work besides this, so be aware that responses may be a little slower than usual. Thank you for your patience.
What is the difference between -BadMateFilter and -MappingQualityFilter in Unifiedgenotyper?
Actually, that's not quite right (but it's not Geraldine's fault since the documentation in the code was wrong). The BadMateFilter removes reads whose mate maps to a different contig than it does.
BadMateFilter applies to read pairs that are not properly paired or have mismatching information. MappingQualityFilter applies to reads that are assigned to a place on the reference with low confidence.
Answers
BadMateFilter applies to read pairs that are not properly paired or have mismatching information. MappingQualityFilter applies to reads that are assigned to a place on the reference with low confidence.
Geraldine Van der Auwera, PhD
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