SNP filtering for haploid genomes

mikawinmikawin Posts: 30Member
edited October 2012 in Ask the GATK team

Hello,

Does the GATK team have any recommendations for filtering SNP data for haploid genomes? Our team works with microbial eukaryotes, both haploid and diploid and we have used the GATK v3 best practices for filtering for the latter. [VQSR was not possible, since we do not have access to a truth/high confidence SNP set.]

Thanks,
Mika

Post edited by Geraldine_VdAuwera on
Tagged:

Best Answer

  • Geraldine_VdAuweraGeraldine_VdAuwera Posts: 8,043Administrator, GATK Dev admin
    edited October 2012 Answer ✓

    Hi Mika,

    See this thread for a relevant discussion. Unfortunately as you'll read there we don't have much experience with non-diploid organisms, and little insight to offer. However you may be able to get some advice from the user community by posting this in the "Ask the community" section of the forum.

    Good luck!

    Post edited by Geraldine_VdAuwera on

    Geraldine Van der Auwera, PhD

Answers

  • Geraldine_VdAuweraGeraldine_VdAuwera Posts: 8,043Administrator, GATK Dev admin
    edited October 2012 Answer ✓

    Hi Mika,

    See this thread for a relevant discussion. Unfortunately as you'll read there we don't have much experience with non-diploid organisms, and little insight to offer. However you may be able to get some advice from the user community by posting this in the "Ask the community" section of the forum.

    Good luck!

    Post edited by Geraldine_VdAuwera on

    Geraldine Van der Auwera, PhD

Sign In or Register to comment.