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The ComputeInsertStatistics utility prints statistics about the data in a binary histogram file.
The printed metrics include the median insert size and robust standard deviation (RSD). The RSD is the width of the central 68% of the insert size distribution.
-I <histogram-file>: The input binary histogram file.
-O <output-file>: Tab-delimited output file (default is stdout).
Geraldine Van der Auwera, PhD